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The therapeutic challenge of highly active MS

The therapeutic challenge of highly active MS
  • Neurology
Multiple sclerosis


17 November 2017




The course describes a challenging clinical case of a women with highly active multiple sclerosis and recurrent treatment failures. Prognostic factors of treatment response and disability progression, as well as switching strategies are also illustrated

This case is aimed to illustrate criteria for the definition of treatment response and treatment switching algorithms in highly active multiple sclerosis. 

The expected outcomes are:

  • Learn how to identify highly active patients
  • Define criteria for treatment response
  • Illustrate pros and contra of orizzontal and vertical treatment switch and of induction and escalation strategies



The therapeutic challenge of highly active MS, made available on and organized by EXCEMED,

is accredited by the European Accreditation Council for Continuing Medical Education (EACCME) to provide the following CME activity for medical specialists.

Each medical specialist should claim only those credits that he/she actually spent in the educational activity. The EACCME is an institution of the European Union of Medical Specialists (UEMS). Only those e-learning materials that are displayed on the UEMS-EACCME website have formally been accredited.

Through an agreement between the European Union of Medical Specialists (UEMS) and the American Medical Association (AMA), physicians may convert EACCME credits to an equivalent

number of AMA PRA Category 1 Credits TM . Information on the process to convert EACCME credit to AMA credit can be found at