This online course prepared by Thomas Müller, MD, focuses on intrathecal immunological players and effectiveness of intrathecal treatments in MS. Professor Müller provides an overview of the main immunologic factors and mechanisms of inflammation in MS and current treatment options. He compares the various serum and cerebrospinal fluid biomarkers of central nervous system inflammation and brain damage. He then looks at the mechanisms of action and efficacy of intrathecal-administered drugs.

By the end of this course participants will:

• Be able to describe the principal immunological players of intrathecal inflammation.
• Understand the value and limitations of present serum and CSF biomarkers of CNS inflammation and brain damage.
• Have a better understanding of the current armamentarium of intrathecal-administered drugs.