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Molecular oncology tumor board in colorectal cancer: Bench to bedside to bench - The virtuous cycle of research

Molecular oncology tumor board in colorectal cancer: Bench to bedside to bench - The virtuous cycle of research
  • Oncology
  • Metastatic colorectal cancer
Practice teaching course by Excemed
Friday, Oct 13 - Saturday, Oct 14 2017
Genoa, Italy

Language

English

Registration status
Closed

Target audiences

Practicing clinicians who have an interest in understanding colorectal cancer biology and building individual competencies in the management of the disease.

Files

Introduction

Access learning resources by clicking the Outcomes tab or scroll down to the Scientific Programme.

Overview

The goal of personalized medicine is to tailor treatments to the patient’s individual biologic profile. In oncology, this concept has been reinvigorated by major achievements in therapeutic and molecular diagnostics. The exponential growth in understanding colorectal cancer biology has led to  recent  advancements  in  therapeutic  strategy  and predictability of added value for patients. The integration of  precision  medicine  into  medical  oncology  is transforming treatment algorithms which may ultimately translate  knowledge  into  daily  clinical  practice,  while leading  to  a  more  collaborative  disease  management approach among disciplines.

Learning objectives

• Recapitulate colorectal cancer biology and select molecular tests of clinical relevance
• Evaluate biomarker-driven strategies and establish a “continuum of care” in patients with colorectal cancer
• Implement the design and interpretation of clinical trials in colorectal cancer

Scientific programme

Friday, 13 October 2017

SESSION I

09.15     Introduction
              
A. Sobrero (Italy)

 
09.30  L1:  Management of advanced colorectal cancer  VIDEO LECTURE
           
A. Sobrero (Italy)


10.00  L2:  Molecular determinants for first-line treatment in mCRC  VIDEO LECTURE
           
C.H. Köhne (Germany)
          This lecture will be graphically recorded  
 

10.30  L3:  Second-line treatment and beyond in mCRC 
           
A. Sobrero (Italy)
          This lecture will be graphically recorded  

11.00  Coffee Break


11.15    Working groups

             Clinical cases solving
             
C.H. Köhne (Germany); F.S. Papadia (Italy); A. Sobrero (Italy)
 

12.45    Question time


13.00    Lunch

SESSION II

14.00  L4: Dominant molecular pathways in CRC  VIDEO LECTURE
           
R. Dienstmann (Spain)


14.30  L5: Tumor heterogeneity  VIDEO LECTURE
           P. Gazzaniga (Italy)
          This lecture will be graphically recorded  


15.00  L6: Colorectal molecular subtypes and beyond  VIDEO LECTURE
         
 R. Dienstmann (Spain)


15.30    Coffee Break


15.45  L7: Tissue sampling bias and liquid biopsy
         
 P. Gazzaniga (Italy)
           This lecture will be graphically recorded  


16.15    Question time


16.30    PATIENT MANAGEMENT
             Molecular oncology & Medical oncology: interprofessional dialogues
             
R. Dienstmann (Spain); P. Gazzaniga (Italy);
             C.H. Köhne (Germany); A. Sobrero (Italy)


17.15    End of the first day 

 

Saturday, 14 October 2017

09.15    Wrap-up time


09.30  L8:  Three versus six months adjuvant chemotherapy in stage III colon cancer
           A. Sobrero (Italy)


10.00  L9:  To treat or not to treat stage II CRC
           C.H. Köhne (Germany)


10.30  Coffee Break


10.45    Working groups
             Clinical cases solving

             C.H. Köhne (Germany); F.S. Papadia (Italy); A. Sobrero (Italy)


11.15  L10:  Evolving clinical trial design in CRC
           R. Dienstmann (Spain)
           This lecture will be graphically recorded  


11.45  L11:  Interpretation of clinical trials results
           A. Sobrero (Italy)
          This lecture will be graphically recorded  


12.15    CLINICAL TRIALS
             Molecular oncology & Medical oncology: interprofessional dialogues

             R. Dienstmann (Spain); P. Gazzaniga (Italy);
             C.H. Köhne (Germany); A. Sobrero (Italy)
             This interprofessional dialogue will be graphically recorded   

13.00    Concluding remarks


             End of the course


             Closing Lunch




 

CME provider

EXCEMED - Excellence in Medical Education

Chair(s)

Speakers

Paola Gazzaniga

Department of Molecular Medicine
Circulating Tumor Cells Unit
La Sapienza University of Rome
Rome, Italy

Rodrigo Dienstmann

Oncology Data Science (ODysSey) Group
Vall d'Hebron Institute of Oncology Barcelona
Barcelona, Spain
Sage Bionetworks
Computational Oncology Group
Seattle, United States
Publication
Oncology
Slide kit
Rodrigo Dienstmann
Oncology
Slide kit
Rodrigo Dienstmann
Oncology
Slide kit
Rodrigo Dienstmann, Paola Gazzaniga, Claus-Henning Köhne, Alberto Sobrero
Oncology
Slide kit
Rodrigo Dienstmann, Paola Gazzaniga, Claus-Henning Köhne, Alberto Sobrero
Oncology
Rodrigo Dienstmann
Oncology
Slide kit
Rodrigo Dienstmann
Oncology
Rodrigo Dienstmann
Oncology
Slide kit
Paola Gazzaniga
Oncology
Video
Paola Gazzaniga
Oncology
Slide kit
Paola Gazzaniga
Oncology
Slide kit
Claus-Henning Köhne
Oncology
Slide kit
Claus-Henning Köhne
Oncology
Slide kit
Claus-Henning Köhne
Oncology
Slide kit
Claus-Henning Köhne, F.S. Papadia, Alberto Sobrero
Oncology
Slide kit
Alberto Sobrero
Oncology
Slide kit
Alberto Sobrero
Oncology
Slide kit
Alberto Sobrero
Oncology