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Implementation of ACC Guidelines in Clinical Practice: An Interactive Symposium

Implementation of ACC Guidelines in Clinical Practice: An Interactive Symposium
  • Endocrinology and metabolism
Symposium by Excemed
Sunday, Dec 2 2018
Cape Town, South Africa



Event format

Learning Journey


The official language of the live intervention is English.

Registration status
Not applicable

Any attendee registered at ICE2018 can attend this Satellite Symposium free of charge.


Adrenocortical carcinoma is a rare disease with a heterogeneous clinical presentation and a median survival of about 3-4 years. The estimated incidence of adult adrenocortical carcinoma is 0.7-2.0 per million per year, are mostly sporadic but may also occur as part of hereditary syndromes. The prognosis varies based on disease stage, histopathology/immunohistochemistry features, surgical resection. The adrenolytic drug mitotane is the main pharmacotherapy for patients with adrenocortical carcinoma. Mitotane acts as an inhibitor of several enzymes involved in the steroidogenesis and has also direct cytotoxic effects on the adrenal cortex. Mitotane is suggested alone or in combination with other chemotherapeutical agents in patients with adrenocortical carcinoma of different stages. However, the heterogeneity of the clinical presentation imposes a personalized approach, balancing benefits with side effects and risks.

This interactive symposium has been implemented to provide attendees with the most recent evidences and recommendations about clinical management of adrenocortical carcinoma. This will be done by discussing real clinical cases with key opinion leaders in the field. Participants will have the opportunity to be engaged and discuss with their colleagues and the faculty the challenges of managing adrenocortical carcinoma at the different stages of the disease.

Learning objectives

By attending the live educational satellite symposium participants will be able to:

  • understand the variable presentation of adrenocortical carcinoma
  • apply adrenocortical carcinoma guidelines in clinical practice
  • increase the confidence in managing Mitotane therapy

Accreditation details

The  symposium  “Implementation  of  ACC  guidelines  in  clinical  practice:  an  interactive symposium” is accredited by South African Medical Association and designated for a maximum of 1 (one) hour of CEU credits (Continuing Education Unit).

Scientific programme

Sunday, December 2                      

13.00  Adrenocortical Carcinoma – initial approach (A. Tabarin, France) SLIDE KIT | VIDEO

13.10  CC1 Localized adrenocortical carcinoma (M. Terzolo, Italy) SLIDE KIT | VIDEO

13.30  CC2 Metastatic adrenocortical carcinoma (T. Else, USA) 

13.50  CC3 Intro Interactive Clinical Case to solve on the EXCEMED Satellite Symposium webpage (M. Terzolo, Italy)

13.55  Take-Home Messages (A. Tabarin)

End of the satellite symposium



Antoine Tabarin

Head of the Department of Endocrinology, Diabetes and Nutrition
University Hospital of Bordeaux Bordeaux
Bordeaux, France

Massimo Terzolo

Head of the Department of Internal Medicine
University of Turin
San Luigi Hospital
Department of Clinical and Biological Sciences
Turin, Italy

Tobias Else

University of Michigan
Division of Metabolism, Endocrinology and Diabetes
Department of Internal Medicine
Ann Arbor, Michigan, United States

Antoine Tabarin
Endocrinology and metabolism
Slide kit
Antoine Tabarin
Endocrinology and metabolism
Slide kit
Antoine Tabarin
Endocrinology and metabolism

Massimo Terzolo
Endocrinology and metabolism
Slide kit
Massimo Terzolo
Endocrinology and metabolism