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Perspective interview - Friedrich Trefz (PKU treatment in adults)

Trefz 150911

PKU treatment in adults, including during pregnancy

1. How does PKU affect adults?

2. What treatment is recommended for adults with PKU?

3. Are adult patients adherent to the diet?

4. What proportion of adult PKU patients are eligible for BH4 treatment?

5. How does BH4 cofactor benefit adult patients?

6. Are there any special populations requiring particular care?

7. Why is phenylalanine control so important in pregnant patients?

8. What treatment should pregnant women receive for PKU?

9. What is the future of PKU management in adults?