Click on any title below to learn more about it.
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Title |
Author |
Status |
Type |
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The double-edged sword of cellular senescence |
Judith Campisi |
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Description
This online video activity, presented by Professor Judith Campisi, discusses cellular senescence as a potent tumor-suppressive
response that arrests the proliferation of potential cancer cells. Professor Campisi presents the background to cellular senescence
and discusses several the reasons for its evolution. She introduces the senescence-associated secretory phenotype (SASP) and
the signalling pathways that drive it.
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Genetic markers of ovarian response |
Manuela Simoni |
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Description
In this online course Manuela Simoni offers a state of the art overview of genetic markers of ovarian response. She introduced
the topic, reviewing the methodology of genetic association study and describing the influences of FSH’s and follicle stimulating
hormone (FSH) receptors’ genetic polymorphisms on reproductive function physiology. Polymorphisms of FSH receptors, anti-Mullerian
hormone (AMH) and AMH receptors and 5,10-methylene-tetrahydrofolate reductase (MTHFR) as markers of response to ovarian stimulation
are then reviewed in depth providing updates on data published and proposing future lines of research.
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Culture media and in vitro embryo development |
Jay Baltz |
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Description
In this online course Jay Baltz discusses the milestones in the history of culture media for embryo development and developments
that have led to the current media for culturing human cleavage-stage embryos.
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Does LH play a role? Defining subgroups who may need LH in ART |
Peter Humaidan |
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Description
In recent years the possible beneficial role of LH supplementation has received increasing attention. This course, starting
from the role of LH in the spontaneous cycle, will analyse the major issues related to the implementation of LH supplementation
in ART, from patient selection and doses to the time of administration.
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Embryo cryopreservation |
Pedro N. Barri |
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Description
In this online course, Pedro Barri discusses the usefulness and outcome of techniques used for embryo cryopreservation, procedures
employed in IVF for fertility preservation in oncology patients and results of embryo cryoreplacement. The course includes
case descriptions that provide practical information on management of fertility preservation in oncology patients.
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Factors affecting implantation |
Harvey J. Kliman |
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Description
This online CME program was produced by Serono Symposia International, Inc.
The goal of this program was to provide physicians, advanced practice nurses, and pharmacists with an understanding of the
role of endometrial development and receptivity for implantation.
Learning objectives
Upon completion of this program, the participant will be able to:
- Describe the steps in blastocyst implantation
- List the best described markers of endometrial development
- Distinguish between the marker patterns of a normal receptive endometrium and an endometrium from a patient with defects in
endometrial receptivity
- Describe the role of cyclins in the mitotic cycle and explain their utility for endometrial assessment
- Discuss critically the potential treatment options for patients with defects in endometrial receptivity
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New trends: IVF in a globalised world |
Ian Cooke |
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Description
Although ART has extended widely in a few nations in the developed world, in most countries access to cycles is limited by
several factors, particularly financial. If one looks at low resource economies the picture is bleak. Not only is access to
ART even more restricted, but there are a number of structural constraints that further limit the introduction of assisted
reproduction in national healthcare systems. In this course Ian Cooke analyses the current global picture of IVF with special
emphasis on the United Nations' Millennium Development Goals.
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Ovulation induction |
Kim L. Thornton; Carol Lesser |
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Description
This online CME course focused on the diagnosis and treatment of ovulatory disorders and is divided into four chapters, each
covering topics important to understanding ovulation. The target audience includes physicians, nurses, pharmacists and other
healthcare professionals interested in ovulation induction.
Learning objectives
Upon completion of this program, the participant will be able to:
- Describe the physiologic process of the human menstrual cycle.
- Describe the process of ovulation, ovulation induction, and augmentation therapy with clomiphene citrate, menotropins, urofollitropin,
recombinant FSH, and adjunct medications.
- Review the impact of age on fertility with appropriate tests available to assess ovarian reserve.
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The azoospermic male: diagnostic and therapeutic options |
Robert D. Oates |
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Description
This program was developed by Serono Symposia International, Inc.
The goal of this program was to provide physicians, nurses, pharmacists and other healthcare practitioners involved in Reproductive
Medicine with the differential diagnosis of azoospermia and to briefly review some of the treatment options available.
Learning objectives
Upon completion of this program, the participant will be able to:
- Describe male reproductive anatomy and function.
- Construct a differential diagnosis of azoospermia based upon the semen volume and pH.
- Subdivide the main diagnostic categories into distinct entities based upon the results of additional tests and physical examination
findings.
- Interpret the main subtypes of pathological testicular histology.
- Devise a therapeutic plan for the azoospermic male.
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The azoospermic male: genetic consideration |
Robert D. Oates |
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Description
This program was developed by Serono Symposia International, Inc.
The goal of this program was to provide physicians, experienced REI nurses, pharmacists, and other healthcare practitioners
involved in Reproductive Medicine with the genetic basis of several disorders that cause male factor infertility. With this
foundation, the practitioner will be able to counsel couples as to possibilities of transmission to their offspring.
Learning objectives
Upon completion of this program, the participant will be able to:
- Describe the basic spermatogenic process.
- Construct a diagram of the Y chromosome and its spermatogenesis regions.
- Coherently synthesize the clinical and genetic aspects of Congenital Bilateral Absence of the Vas Deferens.
- Interpret the consequences of a Y chromosomal microdeletion.
- Devise a genetic diagnostic plan for each of the entities discussed.
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The balancing act: treating hyper and hypo responders |
Victoria M. Maclin |
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Description
Optimal ovarian stimulation requires the ability to “tailor” the stimulation protocol to the particular needs of the patient.
There is no protocol that will be appropriate for every patient. “One size does not fit all!”
The goal of this program was to provide physicians, nurses, pharmacists and other healthcare providers with an understanding
of how to manage hyper and hypo responders.
Learning objectives
Upon completion of this program, the participant will be able to:
- Describe and characterize the three categories of ovarian response
- Identify and interpret tests of ovarian reserve and response
- Describe three ovarian stimulation protocols for the hypo-responder
- Describe three ovarian stimulation protocols for the hyper-responder
- Identify three methods specifically aimed at the prevention of severe Ovarian Hyperstimulation Syndrome (OHSS)
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