User login

We offer our registered users tailored information, free online courses and exclusive content.

You have an old EXCEMED account ...

Our platform has been renewed. All users registered at any of the old websites are kindly requested to reset their password. Why is this?

... or you lost your password?

Search results

  1. Perspective interview - Nicola Longo (PEG-PAL)

    ... is that a PKU patient taking sapropterin will synthesize Tyr from Phe , as a product of the transformation of Phe . With PEG-PAL there is no generation of Tyr so we might need to supplement Tyr for patients treated with the ...

  2. Perspective interview - K Michael Gibson

    ... and we’re very close to that. But, Phe and tyrosine ( Tyr ) are very close in structure, they have very similar “saturation ... we’ve tried so far has still had a slight effect on Tyr . This is a problem because Tyr is the precursor of dopamine, one of ...

  3. Differential diagnosis of PKU and BH4 deficiency

    ... ↑ ↑ ↑ ↑ Phe / Tyr (DBS, P) ↑ ↑ ↑ ↑ ↑ ...

  4. Frequently Asked Questions about PKU

    ... transformation of phenylalanine ( Phe ) into tyrosine ( Tyr ) in the liver. When PAH activity is decreased, Phe tends to ...

  5. Oral communications

    ... on: dose availability of adequate tyrosine (Tyr) and tryptophan (Trp) Phe concentration (specifically the Phe:Tyr and/or Phe:Trp ratios.) Reduced brain dopamine and serotonin ...

  6. Perspective interview - Harvey Levy (PKU Heroes)

    ... with TMS, we measure not only Phe levels but also tyrosine (Tyr), the immediate metabolite of Phe. When a baby has PKU the Tyr levels will be low or certainly not elevated. This allows us to minimise ...

  7. SSIEM Annual Symposium 2012

    ... AAs may be affected. In PKU for example, levels of tyrosine (Tyr), normally produced as a breakdown product of Phe metabolism, may be ...

  8. 5th European Phenylketonuria Group Symposium 'Advances and Challenges in PKU'

    ... secondary reduction of other amino acids in the brain, e.g. Tyr, and renal nitrogen overload were observed, thus requiring other molecules ... in PKU, and after exercise phe levels remain stable while Tyr and Trp seem to get up to normal levels. Further analysis and confirmations ...

  9. 4th European Phenylketonuria Group (EPG) Symposium

    ... additionally presented a study on the capacity of the Phe:Tyr ratios to predict motor-cognitive abilities of PKU children when compared to Phe levels alone. Phe:Tyr ratios were better predictors of cognitive functions, concurrent of ...

  10. Workshop sessions

    ... in follow-up beside absolute Phe level? What is the role of Tyr supplementation? Diet plus sapropterin in clinical practice — ...

Pages