User login

We offer our registered users tailored information, free online courses and exclusive content.

You have an old EXCEMED account ...

Our platform has been renewed. All users registered at any of the old websites are kindly requested to reset their password. Why is this?

... or you lost your password?

Search results

  1. Frequently Asked Questions about PKU

    ... a mother affect her fetus during pregnancy? Can high phenylalanine enter the brain in PKU patients? What is the importance of ... ability to break down an amino acid called Phenylalanine ( Phe ) found in foods containing protein. High Phe may trigger ...

  2. Frequency of blood phenylalanine monitoring and point-of-care home blood phenylalanine monitoring devices

    Blood phenylalanine (Phe) remains the acknowledged biochemical marker for monitoring treatment ... receiving timely feedback about blood Phe results and their level of overall metabolic control. The European PKU guidelines 1 ...

  3. SSIEM Congres report

    ... PKU Measurement of the standard deviation (SD) of blood phenylalanine ( Phe ) levels in patients with PKU may be a useful tool for assessing the ...

  4. Perspective interview - Nicola Longo (PEG-PAL)

    ... Work to evaluate clinically the use of pegylated recombinant phenylalanine ammonia lyase ( PEG-PAL ) as a potential therapy for PKU is ... in those patients who are responsive, their high blood- Phe levels are reduced to more acceptable levels,' the professor said. ...

  5. 4th European Phenylketonuria Group Symposium

    ... Although it is caused in 98% of cases by a mutation in the phenylalanine hydroxylase (PAH) gene, there are more than 600 mutations ... Dr Jahja stressed the importance of a stricter Phe blood level control in the first 12 years of life to achieve normal neurological ...

  6. 5th European Phenylketonuria Group Symposium

    ... and phenotype, according to Prof Ania Muntau4. Because phenylalanine hydroxylase (PAH) is a homotetramer, a dimer of dimers, it is ... competing with Phe on the LAT-1 transporter at that level. Methylaminoisobutyrate showed the best results in animals but was found ...

  7. Perspective interview - Aurora Martinez

    ... by missense mutations. Prof Martinez began working with phenylalanine hydroxylase ( PAH ) as a postdoctoral researcher. Today, now a ... is a spectrum of patients with very different levels of blood- Phe and very different effects of the disease. 'My belief is that there ...