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  1. Perspective interview - Nicola Longo (PEG-PAL)

    Prof Nicola Longo discusses the potential of PEG-PAL therapy Work to evaluate clinically the use of pegylated recombinant phenylalanine ammonia lyase ( PEG-PAL ) as a potential therapy for PKU is ongoing, and Prof Longo provided ...

  2. Perspective interview - Nicola Longo (PEG-PAL: the latest evidence)

    PEG-PAL : the latest evidence Video PEG-PAL: the latest evidence Nicola Longo, USA Specialty area(s) ...

  3. 2014 Annual Multidisciplinary European Phenylketonuria Symposium: PKU a lifetime of challenges

    ... City, USA presented the latest evidence about the use of PEG-PAL in PKU patients. PEG-PAL (pegylated phenylalanine ammonia lyase) is a bacterial enzyme ...

  4. Medical report for 5th EPG Symposium available

    ... on the phase I-II clinical studies performed with rAV- PEG-PAL enzyme substitution therapy for PKU. This approach seemed highly ...

  5. 2014 Annual Multidisciplinary European Phenylketonuria Symposium: PKU a lifetime of challenges

    ... Burlina, Italy, Ivo Barić, Croatia   09.15  PEG-PAL : the latest evidence Nicola Longo, USA 09.40 Pharmacological ...

  6. 5th European Phenylketonuria Group Symposium 'Advances and Challenges in PKU'

    ... Maureen Clearly (UK) 08.30 L4: Clinical trials with the PEG-PAL enzyme substitution Cary O. Harding (USA) 09.00 L5: Novel ...

  7. Interviews with expert presenters

    ... in adults View video interview   PEG-PAL: the latest evidence View video interview   BH4 ...

  8. 5th European Phenylketonuria Group Symposium

    ... to PKU patients.   Advances in PKU management PEG-PAL on trial Prof Cary Harding5 gave an update on the phase I-II ... variabilis pegylated phenylalanine ammonia lyase (rAV-PEG-PAL), enzyme substitution therapy for PKU. Weekly subcutaneous injection ...

  9. SSIEM Congres report

    ... Oral pegylated recombinant phenylalanine ammonia lyase (PEG-PAL) therapy, serving as an adjunct to dietary treatment, has the potential ... by the promising results from stu­dies into injectable PEG-PAL as a treatment for HPA, currently undergoing clinical trials, to ...