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  1. Importance of timely diagnosis of prediabetes and diabetes

    ... 2009, the ADA advocated the use of haemoglobin A1c levels ( HbA1c ) to diagnose diabetes, and recommended the use of an HbA1c of 5.7%–6.4% as being diagnostic of prediabetes. 5 Diabetes is ...

  2. Management of Pre-diabetes in the Asia-Pacific region

    ... laboratory tests (i.e., fasting blood glucose [FPG], HbA1c and/or 75 g oral glucose tolerance test [OGTT]). High risk individuals ... 2-hour OGTT is 140–99 mg/dL (7.8–11.0 mmol/L), and HbA1c is >5.7%. If the initial screening for pre-diabetes is negative, ...

  3. Highlights of the 52nd European Association for the Study of Diabetes

    ... trial in adults with T1D and suboptimal glycaemic control ( HbA1c 7–10%). There were 1398 enrolled patients randomised 3:1 to receive ... to insulin. The primary endpoints were the change in HbA1c , fasting body weight and total insulin dose. A secondary endpoint was ...

  4. Congress Report: 17th American Diabetes Association (ADA) meeting

    ... the mean duration of diabetes was 16.4 years, and mean HbA1c was 8.4%. The primary composite outcome was the first occurrence of an ... P <0.001 for noninferiority). At 2 years, the mean HbA1c was 7.5% in each group, but the mean fasting plasma glucose level was ...

  5. Highlights from the 53rd European Society for the Study of Diabetes (EASD) Annual Meeting

    ... T2D. They found that SGLT2 inhibitor treatment reduced HbA1c concentration (62±13 mmol/mol [7.7±1.2%] versus 59±16 mmol/mol ... pressure (Spearman’s q= 0.319; P =0.031), but not in HbA1c concentration, were correlated with changes in QTc dispersion after ...

  6. Current global guidelines for type 2 diabetes treatment

    ... symptomatic and/or elevated blood glucose levels or HbA1c , consider initiating insulin (as mono- or combination therapy). If ... at maximum tolerated dose does not achieve or maintain the HbA1c target over 3 months, a second oral agent – a glucagon-like peptide-1 ...

  7. The role of SGLT-2 inhibitors in diabetes management and cardiovascular disease risk

    ... inhibitors exert multiple metabolic benefits (decreases in HbA1c, body weight and blood pressure and an increase in high density ... disease. All SGLT2 inhibitors on the market similarly reduce HbA1c, blood pressure and body weight and have a good safety profile. ...

  8. Scientific Highlights: 2015 Asia Pacific conference on cardiometabolic diseases management

    ... than men. Glycaemic control is crucial: just a 1% rise in HbA1c can increase risk of HF by 25%. It is likely that T2DM has a direct ... advantage of intensive control vs. standard control, and HbA1c of <7% offers a worse CV prognosis. The choice of ...

  9. Recommended reading – key published papers from 2017

    ... GLP-1RAs, but for fasting plasma glucose levels and HbA1c , continuous-acting treatments had the greater effect. No ...

  10. Highlights from the 18th American Diabetes Association meeting (ADA), Orlando, USA, June 22–27th 2018

    ... period) was assessed by hyperglycemic clamp. At 6 months, HbA1c levels were reduced transiently from baseline in both groups, but this ...

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