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  1. Diabetes and Metformin

    ... may be mediated by the gut-derived incretin hormone glucagon-like-peptide 1 (GLP-1). GLP-1 is secreted to the circulation after ... insulin secretion from pancreatic β cells and inhibition of glucagon release from pancreatic α cells. 10 In 1998, Lugari et al . ...

  2. Congress Report: 2015 International Diabetes Federation (IDF) World Congress

    ... in advanced stage of development include depot injections of glucagon-like peptide-1 (GLP-1) analogues which last several months and ... peptidase 4 inhibitors. Hybrid peptides of incretins, glucagon analogues and other peptides are in earlier stages of development, and ...

  3. The role of SGLT-2 inhibitors in diabetes management and cardiovascular disease risk

    ... being favoured by the SGLT2 inhibitor-induced stimulation of glucagon secretion. 3 The rise in plasma ketone concentration is small. ...

  4. Congress Report: Highlights from the 76th American Diabetes Association (ADA) Scientific Sessions

    ... Massachusetts General hospital, USA) suggest that including glucagon in an artificial pancreas has the potential to solve some of the ...

  5. European Association for the Study of Diabetes (EASD) conference 2012: Tackling type 2 diabetes

    ... 11 days resulted in reductions in fasting glucose, insulin, glucagon, triglycerides, and free fatty acids, as well as improved glucose ...

  6. EASD Conference 2012: Highlights from the European Society for the Study of Diabetes-EASD 2012

    ... the combination of molecules with coagonist effects, e.g. glucagon+GLP-1 or GIP+GLP-1, is being tested in animal models to reduce ...