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This live educational conference will look at recent evidence in treating hypertension and hypertension-related clinical conditions, with specific focus on coronary artery disease and heart failure. The role of the increased sympathetic activity in the pathogenesis of cardiovascular disease will also be examined, opening discussion on whether heart rate is a target for pharmacological treatment. The role of combination treatment in hypertension and recent novelties in the availability of fixed dose formulations will also be addressed. Clinical case discussions will help round out this symposium by translating results from controlled clinical trials and guidelines into daily clinical practice.