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A journey from the past to the future of multiple sclerosis

A journey from the past to the future of multiple sclerosis
  • Neurology
  • Multiple sclerosis
Regional workshop by Excemed
Tuesday, Aug 22 2017
São Paulo, Brazil




The official language of this live educational workshop will be English.
Simultaneous translation to and from Spanish and Portuguese will be provided.

Registration status

To register for this event, contact

For registration, accommodation and any logistic
inquiry please contact:
Meridiano Congress International (Italy)
Event management Team Leader: Sara Guglielmini
T +39 06 88 595 211 -  F +39 06 88595 234

Registration fee


Target audiences

Neurologists managing MS in Latin America



Access learning resources by clicking the Outcomes tab or by scrolling down to the Scientific Programme.

In joint partnership with TOPEC Global


The clinical journey of multiple sclerosis is moving forward thanks  to  new  immunological  discoveries,  technological innovation,  as  well  as  improvements  in  diagnosis  and treatment. However, experience demonstrates that accurate evaluation of prognostic factors, early treatment, appropriate switching strategies and adherence to treatment guarantee disability  prevention  on  long-term  observation. These crucial elements have led to changes in the characteristics of  MS  populations  with  patients  presenting  less  severe inflammation  and  disability.  This meeting  will retrace the  steps  of  the  MS  journey,  giving an overview  of the immunological  insights, treatment options and goals from the past to the future.The workshop includes two workshops in which experts will discuss clinical cases with participants.

Learning objectives

  • Illustrate the key immunological mechanisms underpinning MS
  • Describe the mechanisms of action of pulsed immunosuppressive treatment
  • Describe the risk/benefit profile of prolonged treatment
  • Illustrate how to manage treatment switches in clinical practice

Scientific programme

08.45                   Welcome and introduction, G. Comi, Italy

08.55                   Local welcome, J. Becker, Brazil                                  

Session I: Old and new immunological insights into MS

09.00    L1:         Peripheral and central deregulation of the immune system in RRMS and PMS, J. Correale, Argentina

09.20    L2:         Maintenance therapies in RRMS: mechanisms of action, rationale and evidence, VIDEO LECTURE (PORTUGUESE)
                           M.R. Papais Alvarenga, Brazil

09.40    L3:         The emerging concept of long-term remission in MS: mechanisms of action, rationale and evidence, VIDEO LECTURE (SPANISH)
                           O. Fernandez, Spain

10.00    L4:         Treatment of progressive MS: why, who, when, how, VIDEO LECTURE G. Comi, Italy

10.20                   Q&A

10.45                   Coffee break

Session II: Old and new risks of treating MS


11.15 L5:             Risks of maintenance therapies: short and long term observation, VIDEO LECTURE (SPANISH) J. Flores, Mexico

11.35 L6:             Risks of treatments with infrequent dosing: short and long term observation, X. Montalban, Spain                     

11.55 L7:             Burden of monitoring  old and new treatments and long-term adherence to monitoring plan, VIDEO LECTURE (PORTUGUESE)
                            A. Pereira Gomes Neto, Brazil

12.15                   Q&A

12.40                   Lunch

Session III – Working groups

13.40 – 15.40  

This session includes parallel working groups, each lasting 1 hour. Participants will be divided into groups and will attend both in rotation.

W1:                     Treatment switching: when and what,  Case Study 1, Case Study 2,  Y. D. Fragoso, Brazil, and G. Comi, Italy

W2:                     MRI monitoring: efficacy and safety, A. Damasceno, Brazil and X. Montalban, Spain

15.40                   Coffee break

Session IV: Old and new MS patient populations and treatment goals


16.10 L8:              Old and new populations: clinical trials and treatment goals, VIDEO LECTURE Y.D.  Fragoso, Brazil

16.30  L9:             Guidelines for MS treatment in Brazil and the rest of the world, VIDEO LECTURE J. Becker, Brazil

16.50 L10:            Patients and doctors: past and future unmet needs in MS, VIDEO LECTURE (SPANISH) C. Navas, Colombia

17.10                     Q&A

17.45                    Wrap up

 End of the workshop

CME provider

EXCEMED  is  a  nonprofit  foundation  dedicated,  for  the  last  four decades,  to    developing    high-quality  medical  education programmes all over the world.

EXCEMED adheres to the guidelines and standards of the European Accreditation Council for Continuing Medical Education (EACCME ®) which states that continuing medical education must be balanced, independent, objective, and scientifically rigorous.


All EXCEMED programmes are organized solely to promote the exchange and dissemination of  scientific  and  medical  information.  No forms of promotional activities are permitted. There may be presentations discussing investigational uses of various products. These views are the responsibility of the named  speakers  and  do  not  represent  an  endorsement  or recommendation on  the  part  of  EXCEMED. 



Oscár Fernandez

Department of Neurology
Hospital Regional Universitario Carlos Haya
Malaga, Spain

Oscár Fernandez

Department of Neurology
Hospital Regional Universitario Carlos Haya
Malaga, Spain

Giancarlo Comi

Department of Neurology
Institute of Experimental Neurology
Vita-Salute San Raffaele University
Milan, Italy

Jorge Correale

Department of Neurology
Raúl Carrea Institute for Neurological Research (FLENI)
Buenos Aires, Argentina

Xavier Montalban

Vall d’Hebron University Hospital
Neurology-Neuroimmunology Department
Multiple Sclerosis Centre of Catalonia (Cemcat)
Barcelona, Spain
St. Michael’s Hospital
Division of Neurology
University of Toronto
Toronto, Canada

Alfredo Damasceno

Neurology Department
University of Campinas Campinas
Campinas, Brazil

Carlos Navas

Demyelinating disease Unit and Multiple Sclerosis
Clinic University Hospital of Colombia
Bogotà, Colombia
Slide kit
Giancarlo Comi
Slide kit
Giancarlo Comi
Slide kit
Alfredo Damasceno
Slide kit
Josè Flores Rivera
Slide kit
Maria Regina Papais Alvarenga
Slide kit
Fragoso Yara Dadalti
Slide kit
Fragoso Yara Dadalti