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Growth Hormone therapy in childhood: lights, shadows and safety

Growth Hormone therapy in childhood: lights, shadows and safety
  • Endocrinology and metabolism
  • Growth disorder
Workshop by Excemed
Sunday, Dec 9 2018
Taiwan

Event format

Lecture
Workshop session
Registration status
Not applicable

To register for this event, contact

Meridiano Congress International 
Project Coordinator: Federica Russetti 
T +39 06 88595 209 - F +39 06 88595 234 
Mobile +39 320 2890444 
federica.russetti@meridiano.it 

Target audiences

This programme is designed for Asian paediatric endocrinologists
scientists and all healthcare professionals involved in managing children with growth hormone disorders.

Files

Introduction

This programme will be live streamed via ClickMeeting.
Follow the sessions from the comfort of your home or office by joining at this link

Overview

Therapy with recombinant human Growth Hormone (rhGH) is widely available and has been the most important treatment for several growth disorders in childhood since 1985. Scientific attention has been greatly focused on growth disorders directly involving the GH-IGF1 system and other genetic syndromes causing pre and post-natal growth insufficiency. The list of growth factors and genes involved in the complex human growth pathway has been increasing, thank to scientific research.

At the same time, medical progress allowed a better treatment of many well-known chronic diseases affecting children since early age. Short stature in adult life is not the only potential consequence in these children, also the glucose/lipid metabolism and bone-muscle system can result compromised. Long-term complications affect quality of life and psychosocial health in young adult life. Many efforts have been delivered by researchers in getting a better understanding of these mechanism and finding potential solutions. rhGH has been proposed in many pathological conditions to normalize growth and prevent metabolic complications, and long-term safety remains a priority which need a steady surveillance. Paediatricians, and paediatric endocrinologists especially, are of primary importance in the multidisciplinary care of these children. They must face with the growth failure and the long-term complication, in cooperation with the other specialists involved in the care of such chronic diseases. Therefore, there is need for an extensive update on the underling pathogenesis affecting GH-IGF1system, and on the most recent evidence about the potential role of rhGh therapy in promoting growth and prevent complications. Discussion of these medical issues is essential for the caregivers to provide their patients with the most innovative care.

The scope of this proposal is to bring together international experts and offer milestones and new insights on the most updated scientific evidence on chronic disease related growth impairment in children and potential benefit and safety of rhGH therapy.

Learning objectives

  • Recognize several chronic conditions impacting on growth hormone-IGF1 axis  
  • Manage rhGh therapy in different conditions and comorbidities
  • Provide patients with more complete information on long-term advantages and safety of rhGH therapy
  • Improve the adherence of patients receiving growth hormone therapy in the light of a more appropriate use of rhGH therapy

Scientific programme

08.30
Welcome and introduction
Fuu-Jen Tsai (Taiwan)


Session I

09.00 Slide kit
L1: Structural pituitary abnormalities and GH deficiency in genetic syndromes
Roland W. Pfäffle (Germany)


09.30 Slide kit
L2: The GH-IGF1 system in Beta-Thalassemia major: long-term follow up and potential benefits of rhGH treatment
Louis C.K. Low (Hong Kong)


10.00 Slide kit
L3: GH in the transition period: manage the change from childhood to adulthood.
Han-Wook Yoo (Korea)


10.30
Panel Discussion


10.45
Coffee break


11.15 Slide kit
L4: Impact of GH therapy during childhood on bone quality and metabolism
Syed Faisal Ahmed (UK)


11.45 Slide kit
L5: rhGH therapy in chronic disease: the state of art on safety
Stefano Cianfarani (Italy)


12.15 Slide kit
L6: How to assess patients’ adherence to rhGH therapy
Aman Bhakti Pulungan (Indonesia)


12.45
Panel discussion


13.00
Lunch


Session II - Working groups

Chairman: Li-Ping Tsai (Taiwan)
Moderators: S.F. Ahmed (UK), L.C.K. Low (Hong Kong), A.B.Pulungan (Indonesia) and H.W. Yoo (Korea)
 

14.00 Slide kit
Clinical case
Roland W. Pfäffle (Germany)
 

14.30
Group discussion


14.50 Slide kit
Clinical Case
Stefano Cianfarani (Italy)

15.20
Group discussion
 

15.40
Concluding remarks
 

16.00
End of the live educational workshop

 

Chair(s)

Roland Pfäeffle

Head of Gastroenterology Department
Laboratory Medicine Clinical Chemistry and Molecular Diagnostics, University of Leipzig
Centre for Paediatric Research Leipzig (CPL)
University of Leipzig
Augustusplatz 10
Leipzig, 04109, Germany

Fuu-Jen Tsai

Department of Pediatrics
China Medical University
Taichung, Taiwan

Li-Ping Tsai

Buddhist Tzu Chi General Hospital
Department of Pediatrics
Taipei, Taiwan
Speakers

Syed Faisal Ahmed

Consultant & Professor in Paediatric Endocrinology
Paediatric Endocrinology
Samson Gemmell Chair of Child Health
Office Block, Ground Floor, Zone 1
Govan Road, Glasgow
Glasgow, G51 4TF, United Kingdom

Stefano Cianfarani

Bambino Gesù Children's Hospital
Department of Systems Medicine
University of Rome Tor Vergata
Rome, Italy

Louis C.K. Low

Department of Paediatrics and Adolescent Medicine
University of Hong Kong
Hong Kong Sanatorium & Hospital
Hong Kong, China

Roland Pfäeffle

Head of Gastroenterology Department
Laboratory Medicine Clinical Chemistry and Molecular Diagnostics, University of Leipzig
Centre for Paediatric Research Leipzig (CPL)
University of Leipzig
Augustusplatz 10
Leipzig, 04109, Germany

Aman Bhakti Pulungan

Department of Child Health
Faculty of Medicine, University of Indonesia
Cipto Mangunkusumo Hospital
Jakarta, Indonesia

Han-Wook Yoo

Pediatrics & Medical Genetic/Genomics Medical Genetics Center
University of Ulsan College of Medicine
Asan Medical Center Children's Hospital
Seul, South Korea
Slide kit
Syed Faisal Ahmed
Endocrinology and metabolism
Slide kit
Stefano Cianfarani
Endocrinology and metabolism
Slide kit
Stefano Cianfarani
Endocrinology and metabolism
Slide kit
Roland Pfäeffle
Endocrinology and metabolism
Slide kit
Roland Pfäeffle
Endocrinology and metabolism
Slide kit
Aman Bhakti Pulungan
Endocrinology and metabolism
Slide kit
Han-Wook Yoo
Endocrinology and metabolism